Professor
Email: zengjing0052@hust.edu.cn
Academic Area: Medicinal Chemistry
Research Interests: Carbohydrate chemistry and carbohydrate drug; Synthesis of bioactive natural products and clinical agents especially oligosaccharides and glycoconjugates.
Academic Degrees
PhD. in Organic Chemistry, 2013, Nanyang Technological University (NTU), Singapore
M.Sc. in Organic Synthesis, 2007, Xiamen University, Xiamen, China
B.Eng. in Chemistry and Chemical Engineering, 2004, Southeast University, Nanjing, China
Professional Experience
Vice Dean (2024-present); School of Pharmacy, HUST
Professor (2018-present); School of Pharmacy, HUST
Assoc. Professor (2014-2018); School of Pharmacy, HUST
Post-doc. (2013-2014); Nanyang Technological University (NTU), Singapore
Project Officer (2008-2009); Nanyang Technological University (NTU), Singapore
Synthesis Researcher (20070-2008) Shanghai ChemExplorer Company
Selected Publications
1. Zeng J.;* Wang R.; Zhang S.; Fang J.; Liu S.; Sun G.; Xu B.; Xiao Y.; Fu D.; Zhang W.; Hu Y.; Wan Q.* Hydrogen-Bonding-Assisted Exogenous Nucleophilic Reagent Effect for β-Selective Glycosylation of Rare 3-Amino Sugars. J. Am. Chem. Soc. 2019, 144, 8509.
2. Zeng J.;* Wang R.; Yao W.; Zhang S.; Sun G.; Liao Z.; Meng L.; Wan Q.* Gold-catalyzed Diversified Synthesis of 3-Aminosugar Analogues of Digitoxin and Digoxin. Org. Chem. Front. 2018. 5, 3391.
3. Zeng J.; Liu Y., Chen W., Zhao X., Meng L., Wan Q.;* Glycosyl Sulfoxides in Glycosylation Reactions. Top. Curr. Chem. (Z), 2018. 37, 27.
4. Zeng J.;* Sun G.; Wang R.; Zhang S.; Teng S.; Liao Z.; Meng L.; Wan Q.* Gold-catalyzed Diversified Synthesis of 3-Aminosugar Analogues of Digitoxin and Digoxin. Org. Chem. Front. 2017. 4, 2450.
Invited contribution in Synthetic Approaches to Natural Products via Catalytic Processes
Organic Chemistry Frontiers HOT articles for 2017
5. Zeng J.;* Sun G.; Yao W.; Zhu Y.; Wang, R.; Cai, L.; Liu, K.; Zhang Q.; Liu, X.-W.; Wan, Q.* 3-Amino-deoxypyranoses in Glycosylation: Diversified Synthesis and Assembly in Oligosaccharides. Angew. Chem. Int. Ed. 2017, 56, 5227
Selected as front cover paper: Angew. Chem. Int. Ed. 2017, 56, 5133
Highlighted by Wiley Advanced Science News China (ASNChina):2017.04.05.
Highlighted by ChemistryViews:2017.04.14.
Highlighted by Wiley Advanced Science News (Chemviews)：2017.04.18.
Highlighted by Chin. J. Org. Chem. 2017,37,1585
Highlighted by X-Mol:
阿达玛斯学术论文优秀奖
6. Zeng J.; Xu Y.; Wang, H.; Meng L.; Wan Q.* Recent Progress on the Synthesis of 2-Deoxy Glycosides. Sci. China Chem., 2017, 60, 1162. (invited).
7. Ma, J.; Zeng, J.; Wan, Q.* “Postligation-Desulfurization: A General Approach for Chemical Protein Synthesis” Topics in Current Chemistry 2015, 363, 57 (invited, IF: 4.464).
8. Zeng, J.#; Ma, J.#; Xiang, S.; Cai, S.; Liu, X. -W.* Stereoselective β-C-Glycosylation via Palladium-Catalyzed Decarboxylative Allylation: Formal Synthesis of Aspergillide A. Angew. Chem. Int. Ed.,2013, 52, 5134. (IF: 11.709) (Highlight in Synfacts 2013, 8, 870)
9. Zeng, J.; Tan, Y. J.; Leow M. L.; Tirtorahardjo, D.; Liu, X. -W.* Facile Access to Cis-2,6-Disubstituted Ddihydrapyranes via Palladium Catalyzed Intramolecular Decarboxylative Allylation: Total Syntheses of (±)-Centrolobine, (+)-Decytospolide A and B. Chem. Eur. J. 2014, 20, 405. (IF: 5.771)
10. Zeng, J.; Zhang, Q.; Zhang, H. K.*; Chen, A.* Synthesis of trans-Dihydroxybutyrolactols as Efficient 4C Building Blocks: Application to the Synthesis of Polyhydroxylated Alkaloids. RSC, Advances, 2013, 3, 20298. (IF: 3.840)
11. Zeng, J.; Tan, Y. J.; Leow, M. L.; Liu, X. -W.* Copper(II)/Iron(III) Co-catalyzed Intermolecular Diamination of Alkynes: Facile Synthesis of Imidazopyridines. Org. Lett. 2012, 14, 4386. (IF: 6.364) (Highlight in Synfacts 2012, 8, 1300.)
12. Zeng, J.; Bai, Y. G.; Ma, J. M.; Cai, S. T.; Liu, X. -W.*, Direct Synthesis of Pyrroles via A Silver Promoted Three-component Reaction Involving an Unsual Imidazole Ring Opening. Chem. Commun. 2011, 47, 12855. (IF: 6.834)
13. Zeng, J.; Vedachalam, S.; Xiang, S. H., Liu, X. -W.*, Direct C-Glycosylation by Coupling of Organotrifluoroborates with Glycosyl Flouorides and Iits Application to The Total Synthesis of (+)-Varitriol. Org. Lett. 2011, 13, 42. (IF: 6. 6.732) (Highlighted in Organic Chemistry Portal, 2012, http://www.organic-chemistry.org /Highlights/2012/16January.shtm)
Cause Taught
Medicinal Chemistry and Experiments of Medicinal Chemistry
Advanced Organic Chemistry
Progress of Pharmaceutical Research
