Prof. Qian Wan E-mail: wanqian@hust.edu.cn Address: 13 Hangkong Road, Wuhan, P. R. of China, 430030 Academic Career: 2014-2023     Vice Dean, School of Pharmacy 2012-            Professor, Huazhong University of Science and Technology 2007-2011     Scientist, Department of Medicinal Chemistry, Amgen Inc, Cambridge, MA, USA 2004-2007     Research Fellow, Memorial Sloan-Kettering Cancer Centre, Prof. Samuel Danishefsky

Education:

2000-2004	Ph.D. in Organic Chemistry	Paris-Sud (XI) University, Orsay, France. Prof. André Lubineau, Prof. Marie-Christine Scherrmann
1999-2000	M.S. in Organic Chemistry	Paris-Sud (XI) University, Orsay, France. Prof. Claudine Augé
1997-1999	Graduate Student in Organic Chemistry	Central China Normal University, China
1993-1997	B.S. in Chemistry	Central China Normal University, Wuhan, China

Professional Experiences:

2020                          Associate Editor of J. Carbohydr. Chem.

2019                          Editorial Board of Carbohydr. Res.

2019                          Secretary, Committee of Glycochemistry, Chinese Chemical Society

2019                          Member, Glycobiological Engineering Committee of Chinese Society of Bioengineering

2018                          Editorial Board of J. Carbohydr. Chem.

2014                          Review Editor of Front. Chem.

Projects:

2021  2025                National Science Fund for Distinguished Young Scholars (No.22025102)

2019-2022                 National Natural Science Foundation of China (No.21877043)

2018-2020                 National Natural Science Foundation of China (No. 21761132014, NSFC-ANR)

2017-2020                 National Natural Science Foundation of China (No.21672077)

2015-2018                 National Natural Science Foundation of China (No.21472054)

2013-2016                 National Natural Science Foundation of China (No.21272082)

2015-2017                 Natural Science Funds of Hubei Province for Distinguished Young Scholars

2015                         Wuhan Creative Talent Development Fund

2014                         Open-end Research Fund of the State Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry

2006                         Mr. and Mrs. Goodwin and Commonwealth Foundation for Cancer Research

Awards:

2020                         WuXi AppTec Life Science and Chmesitry Awards

2020                         Senior Member of Chinese Chemical Society

2019                         Asian Core Program Lectureship Award (from Hong Kong)

2018                         Thieme Chemistry Journals Award

2017                         Zhang Shuzheng Glycoscience Award for Outstanding Young Glycoscientist by Chinese Society of Biotechnology: Glycobiotechnology Committee

2017                         Asian Core Program Lectureship Award (from Taiwan)

2017                         Asian Core Program Lectureship Award (from Singapore)

2017                         The 4th Adamas Acamdemic Paper Awards-Excellence Award

2015                         7th Asian Community of Glycoscience and Glycotechnology Conference Best Poster Award, Miyagi, Japan

2011                         Amgen First Green Chemistry in Medicinal Chemistry Award

2000-2004                 “Eiffel Scholarship” the French Ministry of Foreign Affairs and European Affairs

Selected Publications：

1. Xiao, X.; Zeng, J.; Fang, J.; Sun, J.; Li, T.; Song, Z.; Cai, L.;  Wan, Q.* “One-pot Relay Glycosylation” J. Am. Chem. Soc. 2020, 142, 5498.

2. Meng, L.; Wu, P.; Fang, J.; Xiao, Y.; Xiao, X.; Tu, G.; Ma, X.; Teng, S.; Zeng, J.; Wan, Q.* “Glycosylation Enabled by Successive Rhodium(II) and Brønsted Acid Catalysis” J. Am. Chem. Soc. 2019, 141, 11775.

3. Zeng, J.;* Wang, R.; Zhang, S.; Sun, G.; Xu, B.; Xiao, Y.; Fu, D.; Zhang, W.; Hu, Y.; Wan, Q.* “Hydrogen Bonding Assisted Exogenous Nucleophilic Reagent Effect for b-Selective Glycosylation of Rare 3-Amino Sugars” J. Am. Chem. Soc. 2019, 141, 8509.

4. Zeng, J.*; Sun, G.; Yao, W.; Zhu, Y.; Wang, R.; Cai, L.; Liu, K.; Zhang, Q.; Liu, X.; Wan, Q.* “3-Aminodeoxypyranoses in Glycosylation: Diversity-Oriented Synthesis and Assembly in Oligosaccharides” Angew. Chem. Int. Ed. 2017, 56, 5227.

5. Xiao, X.; Zhao, Y.; Shu, P.; Zhao, X.; Liu, Y.; Sun, J.; Zhang, Q.; Zeng, J.; Wan, Q.* “Remote Activation of Disarmed Thioglycosides in Latent-Active Glycosylation via Interrupted Pummerer Reaction” J. Am. Chem. Soc. 2016, 138, 13402.

6. Shu, P.; Xiao, X.; Zhao, Y.; Tao, J.; Wang, H.; Lu, Z.; Yao, G.; Zeng, J.; Wan, Q.* “Interrupted Pummerer Reaction in Latent-Active Glycosylation: A Novel Type of Glycosyl Donors with Recyclable and Regenerative Leaving Group” Angew. Chem. Int. Ed. 2015, 54, 14432.

Patents:

3. Wan, Q.; Shu, P.; Zeng, J.; Zhao, Y. “Process for synthesis of glycosyl mercaptan and auranofin” Faming Zhuanli Shenqing. ZL. 201410459125.0

2. Danishefsky, S. J.; Zhu, J.; Wan, Q.; Jeon, I.; Kim, W.; Nagorny, P.; Lee, D.; Livingston, P.; Ragupathi, G. “Glycopeptide constructs and uses thereof”. US2011/0229510 A1.

1. Danishefsky, S. J.; Warren, J. D.; Chen, J.; Wu, B.; Chen, G.; Wan, Q.; Tan, Z.; Kan, C.; Yuan. Y.; Hua, Z.; Ranganathan, K.; Trzupek, J. D. “Preparation of homogeneous erythropoietin and other peptides and proteins” US2010/0081786 A1.